Paralysis results from the destruction of neuronal cells in the spinal ganglia. It may also affect the vestibular nuclei, the cerebellar vermis, and the deep cerebellar nuclei. Inflammation associated with nerve cell destruction alters the color of gray matter in the spinal column, making the affected area appear swollen. In addition, other destructive changes in the forebrain region and hypothalamus may occur. These neurological abnormalities are not fully understood, but it is important to note that most cases will develop a partial or complete paralysis.
If left untreated, serious side effects can occur
Infection with polio is usually contracted through contaminated water. The bacterium causes severe paralysis. If this infection is left untreated, it can lead to serious side effects. In some rare cases, the infection can extend to the brainstem or higher structures of the nervous system. The affected person will need mechanical assistance to breathe. In some severe cases, a child may even lose the ability to walk.
Similar to common viral infections
The biphasic illness is characterized by spinal paralytic poliomyelitis. The first phase of poliomyelitis, abortive polomyelitis, recovers from the disease. A second, more severe phase occurs, after two to five days of recovery. The symptoms of cVDPV in this phase are similar to those of a typical viral infection, except that the virus does not infect the central nervous system. After this, the victim regains their strength and is able to move freely.
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